8HCC

Crystal structure of mTREX1-RNA product complex (AMP)

8HCC の概要

• エントリーDOI: 10.2210/pdb8hcc/pdb
• 分子名称: Three-prime repair exonuclease 1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: trex1, deddh exonuclease, dnase, rnase, amp, hydrolase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 121205.88

構造登録者

Hsiao, Y.Y.,Huang, K.W.,Wu, C.Y. (登録日: 2022-11-01, 公開日: 2023-11-08, 最終更新日: 2023-12-13)

• 主引用文献: Huang, K.W.,Wu, C.Y.,Toh, S.I.,Liu, T.C.,Tu, C.I.,Lin, Y.H.,Cheng, A.J.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y.; Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids.; Nucleic Acids Res., 51:11927-11940, 2023; PubMed: 37870446; DOI: 10.1093/nar/gkad910

実験手法

X-RAY DIFFRACTION (2 Å)