8HB5
Crystal structure of Mincle in complex with HD-275
Summary for 8HB5
Entry DOI | 10.2210/pdb8hb5/pdb |
Descriptor | C-type lectin domain family 4 member E, CALCIUM ION, (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol, ... (4 entities in total) |
Functional Keywords | innate immunity, c-type lectin receptors, mycobacterium leprae, immune system |
Biological source | Bos taurus (cattle) |
Total number of polymer chains | 1 |
Total formula weight | 17757.94 |
Authors | |
Primary citation | Ishizuka, S.,van Dijk, J.H.M.,Kawakita, T.,Miyamoto, Y.,Maeda, Y.,Goto, M.,Le Calvez, G.,Groot, L.M.,Witte, M.D.,Minnaard, A.J.,van der Marel, G.A.,Ato, M.,Nagae, M.,Codee, J.D.C.,Yamasaki, S. PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. Acs Cent.Sci., 9:1388-1399, 2023 Cited by PubMed: 37521780DOI: 10.1021/acscentsci.3c00040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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