8GX3

The crystal structure of human Calpain-1 protease core in complex with 14c

Summary for 8GX3

• Entry DOI: 10.2210/pdb8gx3/pdb
• Descriptor: Calpain-1 catalytic subunit, N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: human protease, calpain-1, antiviral inhibitor, 14a, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 82620.71

Authors

Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z. (deposition date: 2022-09-18, release date: 2023-09-20)

• Primary citation: Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z.; The crystal structure of human Calpain-1 protease core in complex with 14c; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.99 Å)