8GUW
Structure of Aurora Kinase A in complex with activator peptide
Summary for 8GUW
Entry DOI | 10.2210/pdb8guw/pdb |
Descriptor | Peptide from Centrosomal protein of 192 kDa,Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | complex, kinase, cytosolic protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 106623.29 |
Authors | Lee, I.-G.,Park, J. (deposition date: 2022-09-13, release date: 2023-05-31, Last modification date: 2023-11-29) |
Primary citation | Park, J.G.,Jeon, H.,Shin, S.,Song, C.,Lee, H.,Kim, N.K.,Kim, E.E.,Hwang, K.Y.,Lee, B.J.,Lee, I.G. Structural basis for CEP192-mediated regulation of centrosomal AURKA. Sci Adv, 9:eadf8582-eadf8582, 2023 Cited by PubMed: 37083534DOI: 10.1126/sciadv.adf8582 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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