8GTJ
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
Summary for 8GTJ
Entry DOI | 10.2210/pdb8gtj/pdb |
Descriptor | Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8 (3 entities in total) |
Functional Keywords | complex, effector, pyroptosis, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 149938.14 |
Authors | |
Primary citation | Zhong, X.,Zeng, H.,Zhou, Z.,Su, Y.,Cheng, H.,Hou, Y.,She, Y.,Feng, N.,Wang, J.,Shao, F.,Ding, J. Structural mechanisms for regulation of GSDMB pore-forming activity. Nature, 616:598-605, 2023 Cited by PubMed: 36991125DOI: 10.1038/s41586-023-05872-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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