8GJU

Crystal structure of human methylmalonyl-CoA mutase (MMUT) in complex with methylmalonic acidemia type A protein (MMAA), coenzyme A, and GDP

8GJU の概要

• エントリーDOI: 10.2210/pdb8gju/pdb
• 分子名称: Methylmalonic aciduria type A protein, mitochondrial, Methylmalonyl-CoA mutase, mitochondrial, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, isomerase, gtpase, g-protein, cobalamin, vitamin b12, transport, organometallic cofactor, isomerase-hydrolase complex, isomerase/hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 491855.50

構造登録者

Mascarenhas, R.M.,Ruetz, M.,Gouda, H.,Yaw, M.,Banerjee, R. (登録日: 2023-03-16, 公開日: 2023-08-09, 最終更新日: 2024-05-22)

• 主引用文献: Mascarenhas, R.,Ruetz, M.,Gouda, H.,Heitman, N.,Yaw, M.,Banerjee, R.; Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.; Nat Commun, 14:4332-4332, 2023; PubMed: 37468522; DOI: 10.1038/s41467-023-40077-4

実験手法

X-RAY DIFFRACTION (2.79 Å)