8GF2

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies eCR3022.20 and CC12.3

8GF2 の概要

• エントリーDOI: 10.2210/pdb8gf2/pdb
• 分子名称: Spike protein S1, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... (7 entities in total)
• 機能のキーワード: antibody, sars-cov-2, sars-cov, coronavirus, spike, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 242179.53

構造登録者

Yuan, M.,Zhu, X.,Wilson, I.A. (登録日: 2023-03-07, 公開日: 2023-08-23)

• 主引用文献: Zhao, F.,Yuan, M.,Keating, C.,Shaabani, N.,Limbo, O.,Joyce, C.,Woehl, J.,Barman, S.,Burns, A.,Tran, Q.,Zhu, X.,Ricciardi, M.,Peng, L.,Smith, J.,Huang, D.,Briney, B.,Sok, D.,Nemazee, D.,Teijaro, J.R.,Wilson, I.A.,Burton, D.R.,Jardine, J.G.; Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.; Sci.Signal., 16:eabk3516-eabk3516, 2023; PubMed: 37582161; DOI: 10.1126/scisignal.abk3516

実験手法

X-RAY DIFFRACTION (2.851 Å)