8GCR
HPV16 E6-E6AP-p53 complex
Summary for 8GCR
Entry DOI | 10.2210/pdb8gcr/pdb |
EMDB information | 29941 |
Descriptor | Maltose/maltodextrin-binding periplasmic protein,Protein E6, Cellular tumor antigen p53, Ubiquitin-protein ligase E3A, ... (4 entities in total) |
Functional Keywords | complex, hpv, ubiquitin ligase, tumor suppressor, viral protein |
Biological source | Escherichia coli O157:H7 More |
Total number of polymer chains | 3 |
Total formula weight | 190336.02 |
Authors | Bratkowski, M.A.,Wang, J.C.K.,Hao, Q.,Nile, A.H. (deposition date: 2023-03-02, release date: 2024-03-06) |
Primary citation | Wang, J.C.K.,Baddock, H.T.,Mafi, A.,Foe, I.T.,Bratkowski, M.,Lin, T.Y.,Jensvold, Z.D.,Preciado Lopez, M.,Stokoe, D.,Eaton, D.,Hao, Q.,Nile, A.H. Structure of the p53 degradation complex from HPV16. Nat Commun, 15:1842-1842, 2024 Cited by PubMed: 38418456DOI: 10.1038/s41467-024-45920-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.38 Å) |
Structure validation
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