8GCR
HPV16 E6-E6AP-p53 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltose/maltodextrin-binding periplasmic protein,Protein E6 | polymer | 541 | 61190.6 | 1 | UniProt (P0AEY0) UniProt (P03126) Pfam (PF01547) Pfam (PF00518) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli O157:H7 | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP |
2 | B | Cellular tumor antigen p53 | polymer | 220 | 24643.9 | 1 | UniProt (P04637) Pfam (PF00870) In PDB | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
3 | R | Ubiquitin-protein ligase E3A | polymer | 903 | 104305.3 | 1 | UniProt (Q05086) Pfam (PF16558) Pfam (PF00632) In PDB | Homo sapiens (human) | E6AP ubiquitin-protein ligase,HECT-type ubiquitin transferase E3A,Human papillomavirus E6-associated protein,Oncogenic protein-associated protein E6-AP,Renal carcinoma antigen NY-REN-54 |
4 | A, B | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: -381 - -12 (UniProt: P0AEY0)
A: 1 - 158 (UniProt: P03126)
B: 94 - 312 (UniProt: P04637)
R: 1 - 875 (UniProt: Q05086)
PDB | External Database | Details |
---|---|---|
Met -382 | - | initiating methionine |
Gly -11 | - | linker |
Gly -10 | - | linker |
Gly -9 | - | linker |
Gly -8 | - | linker |
Ser -7 | - | linker |
Glu -6 | - | linker |
Asn -5 | - | linker |
Leu -4 | - | linker |
Tyr -3 | - | linker |
Phe -2 | - | linker |
Gln -1 | - | linker |
Gly 0 | - | linker |
PDB | External Database | Details |
---|---|---|
Ser 87 | Cys 87 | engineered mutation |
Ser 104 | Cys 104 | engineered mutation |
Ser 118 | Cys 118 | engineered mutation |
Ser 147 | Cys 147 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 93 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Glu 876 | - | expression tag |
Asn 877 | - | expression tag |
Leu 878 | - | expression tag |
Tyr 879 | - | expression tag |
Phe 880 | - | expression tag |
Gln 881 | - | expression tag |
Gly 882 | - | expression tag |
His 883 | - | expression tag |
His 884 | - | expression tag |
His 885 | - | expression tag |
His 886 | - | expression tag |
His 887 | - | expression tag |
His 888 | - | expression tag |
Gly 889 | - | expression tag |
Leu 890 | - | expression tag |
Asn 891 | - | expression tag |
Asp 892 | - | expression tag |
Ile 893 | - | expression tag |
Phe 894 | - | expression tag |
Glu 895 | - | expression tag |
Ala 896 | - | expression tag |
Gln 897 | - | expression tag |
Lys 898 | - | expression tag |
Ile 899 | - | expression tag |
Glu 900 | - | expression tag |
Trp 901 | - | expression tag |
His 902 | - | expression tag |
Glu 903 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 190139.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 196.2 | |
All* | Total formula weight | 190336.0 |