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8FXY

Cryo-EM structure of cowpox virus M2 in complex with human B7.2 (hexameric ring)

Summary for 8FXY
Entry DOI10.2210/pdb8fxy/pdb
EMDB information29548
DescriptorCPXV040 protein, T-lymphocyte activation antigen CD86, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordspoxvirus m2 protein, opg038, t-cell costimulation, poxviral immune evasion domain pie, b7.2, structural genomics, csgid, viral protein
Biological sourceCowpox virus (Brighton Red)
More
Total number of polymer chains12
Total formula weight294854.91
Authors
Elliott, J.I.,Adams, L.J.,Nelson, C.A.,Fremont, D.H. (deposition date: 2023-01-25, release date: 2025-02-05)
Primary citationElliott, J.I.,Adams, L.J.,Jethva, P.N.,Gross, M.L.,Nelson, C.A.,Fremont, D.H.
Structure basis of poxvirus mediated sabotage of T-cell costimulation
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.34 Å)
Structure validation

231564

PDB entries from 2025-02-19

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