8FXY
Cryo-EM structure of cowpox virus M2 in complex with human B7.2 (hexameric ring)
Summary for 8FXY
Entry DOI | 10.2210/pdb8fxy/pdb |
EMDB information | 29548 |
Descriptor | CPXV040 protein, T-lymphocyte activation antigen CD86, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | poxvirus m2 protein, opg038, t-cell costimulation, poxviral immune evasion domain pie, b7.2, structural genomics, csgid, viral protein |
Biological source | Cowpox virus (Brighton Red) More |
Total number of polymer chains | 12 |
Total formula weight | 294854.91 |
Authors | Elliott, J.I.,Adams, L.J.,Nelson, C.A.,Fremont, D.H. (deposition date: 2023-01-25, release date: 2025-02-05) |
Primary citation | Elliott, J.I.,Adams, L.J.,Jethva, P.N.,Gross, M.L.,Nelson, C.A.,Fremont, D.H. Structure basis of poxvirus mediated sabotage of T-cell costimulation To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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