8FW5
Chimeric HsGATOR1-SpGtr-SpLam complex
Summary for 8FW5
Entry DOI | 10.2210/pdb8fw5/pdb |
EMDB information | 29497 |
Descriptor | GATOR complex protein DEPDC5, GUANOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... (12 entities in total) |
Functional Keywords | mtor complex 1 (mtorc1), rag gtpase, gtr gtpase, lamtor, gator1, nutrient sensing, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 451146.47 |
Authors | Tettoni, S.D.,Egri, S.B.,Doxsey, D.D.,Ouch, C.,Chang, J.,Song, K.,Xu, C.,Shen, K. (deposition date: 2023-01-20, release date: 2023-07-26, Last modification date: 2023-09-20) |
Primary citation | Tettoni, S.D.,Egri, S.B.,Doxsey, D.D.,Veinotte, K.,Ouch, C.,Chang, J.Y.,Song, K.,Xu, C.,Shen, K. Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing. Structure, 31:1065-1076.e5, 2023 Cited by PubMed: 37453417DOI: 10.1016/j.str.2023.06.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
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