8FO2
Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 monomer state
Summary for 8FO2
Entry DOI | 10.2210/pdb8fo2/pdb |
EMDB information | 29339 |
Descriptor | Ras-related protein Rab-7L1, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | cryo-em, parkinson's disease, kinase, lrrk2, rab gtpases, activation, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 308163.61 |
Authors | |
Primary citation | Zhu, H.,Tonelli, F.,Turk, M.,Prescott, A.,Alessi, D.R.,Sun, J. Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382:1404-1411, 2023 Cited by PubMed: 38127736DOI: 10.1126/science.adi9926 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.13 Å) |
Structure validation
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