8FLR
Human PTH1R in complex with PTHrP and Gs
Summary for 8FLR
Entry DOI | 10.2210/pdb8flr/pdb |
EMDB information | 29283 29284 29285 29286 29287 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, agonist, hormone, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 177141.73 |
Authors | Cary, B.P.,Belousoff, M.J.,Piper, S.J.,Wootten, D.,Sexton, P.M. (deposition date: 2022-12-22, release date: 2023-04-26, Last modification date: 2023-06-14) |
Primary citation | Cary, B.P.,Gerrard, E.J.,Belousoff, M.J.,Fletcher, M.M.,Jiang, Y.,Russell, I.C.,Piper, S.J.,Wootten, D.,Sexton, P.M. Molecular insights into peptide agonist engagement with the PTH receptor. Structure, 31:668-676.e5, 2023 Cited by PubMed: 37148874DOI: 10.1016/j.str.2023.04.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
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