8FJM
Crystal Structure of the Trypanosoma brucei DOT1A histone H3K76 methyltransferase in complex with AdoHcy - P212121 space group
Summary for 8FJM
Entry DOI | 10.2210/pdb8fjm/pdb |
Descriptor | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (6 entities in total) |
Functional Keywords | histone lysine methyltransferase, histone-modifying enzyme, dot1a, trypanosoma brucei, adohcy complex, transferase |
Biological source | Trypanosoma brucei brucei TREU927 |
Total number of polymer chains | 2 |
Total formula weight | 59690.36 |
Authors | |
Primary citation | Frisbie, V.S.,Hashimoto, H.,Xie, Y.,Baeza, J.,Nguyen, T.,Yuan, Z.,Garcia, B.A.,Debler, E.W. Structure and Mechanism of the atypical Trypanosoma brucei DOT1A histone H3K76 methyltransferase To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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