8FIK

APOBEC3A E72A inactive mutant in complex with ATTC-hairpin DNA substrate

Summary for 8FIK

• Entry DOI: 10.2210/pdb8fik/pdb
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3A, DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*TP*TP*CP*GP*AP*TP*GP*GP*G)-3'), ZINC ION, ... (7 entities in total)
• Functional Keywords: apobec, apobec3a, a3a, cancer, dna, mutation, cytidine deaminase, hairpin dna, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 56860.96

Authors

Harjes, S.,Jameson, G.B.,Harjes, E.,Filichev, V.V.,Kurup, H.M. (deposition date: 2022-12-16, release date: 2023-09-06)

• Primary citation: Harjes, S.,Kurup, H.M.,Filichev, V.,Harjes, E.,Jameson, G.B.; DNA-based inhibitors restrict mutagenic activity of APOBEC3 in cells; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.912 Å)