8FIK
APOBEC3A E72A inactive mutant in complex with ATTC-hairpin DNA substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA dC->dU-editing enzyme APOBEC-3A | polymer | 199 | 22983.0 | 2 | UniProt (P31941) Pfam (PF05240) | Homo sapiens (human) | A3A,Phorbolin-1 |
| 2 | C, D (D, H) | DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*TP*TP*CP*GP*AP*TP*GP*GP*G)-3') | polymer | 16 | 4874.2 | 2 | Homo sapiens | ||
| 3 | E, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | G, K, L (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | H (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 7 | M, N, O, P (A, B, D, H) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: P31941)
| PDB | External Database | Details |
|---|---|---|
| Ala 72 | Glu 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55714.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1146.7 | |
| All* | Total formula weight | 56861.0 |
