8F8M

LRH-1 bound to small molecule Tet and fragment of coactivator Tif2

8F8M の概要

• エントリーDOI: 10.2210/pdb8f8m/pdb
• 分子名称: Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, (1~{R},3~{a}~{R},6~{a}~{R})-4-phenyl-3~{a}-(1-phenylethenyl)-5-[9-(1~{H}-1,2,3,4-tetrazol-5-yl)nonyl]-2,3,6,6~{a}-tetrahydro-1~{H}-pentalen-1-ol, ... (4 entities in total)
• 機能のキーワード: lrh-1, nr5a2, nuclear receptor, liver receptor homolog-1, nuclear protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30607.39

構造登録者

Cato, M.L.,Ortlund, E.A. (登録日: 2022-11-22, 公開日: 2023-11-29)

• 主引用文献: Cato, M.L.,Abraham, S.M.,Spurlin, R.M.,Flynn, A.R.,Colucci, J.K.,D'Agostino, E.H.,Johnson, A.M.,Jui, N.T.,Ortlund, E.A.; Isosteric improvements to liver receptor homolog-1 small molecule modulators; To Be Published,

実験手法

X-RAY DIFFRACTION (2.6 Å)