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8F79

LRRC8A(T48D):C conformation 2 top focus

Summary for 8F79
Entry DOI10.2210/pdb8f79/pdb
Related8F74 8F75 8F77 8F7B 8F7D 8F7E 8F7J
EMDB information28894 28895 28897 28898 28901 28903 28904 28905
DescriptorVolume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... (4 entities in total)
Functional Keywordsion channel, volume-regulation, membrane protein
Biological sourceMus musculus (house mouse)
More
Total number of polymer chains6
Total formula weight633993.60
Authors
Kern, D.M.,Brohawn, S.G. (deposition date: 2022-11-18, release date: 2023-03-08, Last modification date: 2023-07-05)
Primary citationKern, D.M.,Bleier, J.,Mukherjee, S.,Hill, J.M.,Kossiakoff, A.A.,Isacoff, E.Y.,Brohawn, S.G.
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
Nat.Struct.Mol.Biol., 30:841-852, 2023
Cited by
PubMed: 36928458
DOI: 10.1038/s41594-023-00944-6
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.15 Å)
Structure validation

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