8F79
LRRC8A(T48D):C conformation 2 top focus
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | polymer | 911 | 105544.1 | 5 | UniProt (Q80WG5) UniProt (P0ABE7) Pfam (PF12534) Pfam (PF07361) Pfam (PF13855) In PDB | Mus musculus (house mouse) | Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo,Cytochrome b-562 |
2 | F | Volume-regulated anion channel subunit LRRC8C | polymer | 813 | 93624.6 | 1 | UniProt (Q8R502) Pfam (PF12534) Pfam (PF13855) In PDB | Mus musculus (house mouse) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C |
3 | A, B, C, D, E... | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 17 | Chemie (PEE) | |||
4 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 68 (UniProt: Q80WG5)
A, B, C, D, E: 68 - 72 (UniProt: P0ABE7)
A, B, C, D, E: 72 - 810 (UniProt: Q80WG5)
F: 1 - 803 (UniProt: Q8R502)
PDB | External Database | Details |
---|---|---|
Asp 48 | Thr 48 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Trp 68 | Met 29 | conflict |
Ile 72 | His 124 | conflict |
PDB | External Database | Details |
---|---|---|
Leu 72 | Pro 90 | conflict |
Ser 811 | - | expression tag |
Asn 812 | - | expression tag |
Ser 813 | - | expression tag |
Leu 814 | - | expression tag |
Glu 815 | - | expression tag |
Val 816 | - | expression tag |
Leu 817 | - | expression tag |
Phe 818 | - | expression tag |
Gln 819 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 804 | - | expression tag |
Asn 805 | - | expression tag |
Ser 806 | - | expression tag |
Glu 807 | - | expression tag |
Asn 808 | - | expression tag |
Leu 809 | - | expression tag |
Tyr 810 | - | expression tag |
Phe 811 | - | expression tag |
Gln 812 | - | expression tag |
Gly 813 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 621345.0 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 12648.6 | |
All* | Total formula weight | 633993.6 |