8F3K

Anti-CRISPR protein AcrIIC5 inhibits CRISPR-Cas9 by acting as a DNA mimic

Summary for 8F3K

• Entry DOI: 10.2210/pdb8f3k/pdb
• Descriptor: ACRIIC5Nch, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMMONIUM ION, ... (5 entities in total)
• Functional Keywords: anti-crispr, crispr-cas, cas9, inhibition, protein binding
• Biological source: Neisseria chenwenguii
• Total number of polymer chains: 1
• Total formula weight: 15003.36

Authors

Shah, M.,Sungwon, H.,Davidson, A.R.,Maxwell, K.L.,Moraes, T.F. (deposition date: 2022-11-10, release date: 2023-03-08, Last modification date: 2023-04-12)

• Primary citation: Hwang, S.,Shah, M.,Garcia, B.,Hashem, N.,Davidson, A.R.,Moraes, T.F.,Maxwell, K.L.; Anti-CRISPR Protein AcrIIC5 Inhibits CRISPR-Cas9 by Occupying the Target DNA Binding Pocket.; J.Mol.Biol., 435:167991-167991, 2023; PubMed: 36736884; DOI: 10.1016/j.jmb.2023.167991

Experimental method

X-RAY DIFFRACTION (2.1 Å)