8F09

Crystal structure of a trimethoprim-resistant dihydrofolate reductase (DHFR) enzyme from an uncultured soil bacterium

8F09 の概要

• エントリーDOI: 10.2210/pdb8f09/pdb
• 分子名称: Dihydrofolate reductase, SULFATE ION (3 entities in total)
• 機能のキーワード: structural genomics, center for structural biology of infectious diseases, csbid, oxidoreductase, antimicrobial resistance, antibiotic resistance, trimethoprim, dhfr, dihydrofolate reductase
• 由来する生物種: uncultured bacterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38932.13

構造登録者

Stogios, P.J.,Evdokimova, D.,Borek, D.,Di Leo, R.,Semper, C.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID) (登録日: 2022-11-02, 公開日: 2022-11-16, 最終更新日: 2023-10-25)

• 主引用文献: Stogios, P.J.; Crystal structure of a trimethoprim-resistant dihydrofolate reductase (DHFR) enzyme from an uncultured soil bacterium; To Be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)