8EZ9

Dimeric complex of DNA-PKcs

Summary for 8EZ9

Entry DOI	10.2210/pdb8ez9/pdb
EMDB information	28731 28734
Descriptor	unknown region of DNA-PKcs, DNA-dependent protein kinase catalytic subunit (2 entities in total)
Functional Keywords	dimer, kinase, complex, nhej, dna binding protein
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	942786.66
Authors	Chen, S.,He, Y. (deposition date: 2022-10-31, release date: 2023-06-14, Last modification date: 2024-06-19)
Primary citation	Chen, S.,Vogt, A.,Lee, L.,Naila, T.,McKeown, R.,Tomkinson, A.E.,Lees-Miller, S.P.,He, Y. Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. Sci Adv, 9:eadg2838-eadg2838, 2023 Cited by PubMed: 37256947 DOI: 10.1126/sciadv.adg2838 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.67 Å)

Structure validation