8EJM

Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch

Summary for 8EJM

• Entry DOI: 10.2210/pdb8ejm/pdb
• Descriptor: ATP-dependent RNA helicase DHX15, SURP and G-patch domain-containing protein 1, ADENOSINE-5'-DIPHOSPHATE, ... (8 entities in total)
• Functional Keywords: complex, helicase, splicing factor, rna binding protein, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 87723.13

Authors

Huang, J.,Tong, L. (deposition date: 2022-09-17, release date: 2022-12-14, Last modification date: 2023-10-25)

• Primary citation: Zhang, J.,Huang, J.,Xu, K.,Xing, P.,Huang, Y.,Liu, Z.,Tong, L.,Manley, J.L.; DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.; Proc.Natl.Acad.Sci.USA, 119:e2216712119-e2216712119, 2022; PubMed: 36459648; DOI: 10.1073/pnas.2216712119

Experimental method

X-RAY DIFFRACTION (1.8 Å)