8EFJ
A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds
Summary for 8EFJ
Entry DOI | 10.2210/pdb8efj/pdb |
Descriptor | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, (4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide, ... (4 entities in total) |
Functional Keywords | c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 1 |
Total formula weight | 43267.76 |
Authors | |
Primary citation | Park, H.,Feng, Y. A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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