8EFF

CryoEM of the soluble OPA1 tetramer from the GDP-AlFx bound helical assembly on a lipid membrane

Summary for 8EFF

Entry DOI	10.2210/pdb8eff/pdb
EMDB information	28063
Descriptor	Dynamin-like 120 kDa protein, form S1, GUANOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, ... (5 entities in total)
Functional Keywords	gtpase, dynamin-family protein, mitochondrial fusion protein, mitochondria, optic atrophy, lipid binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	359488.38
Authors	Nyenhuis, S.B.,Wu, X.,Stanton, A.E.,Strub, M.P.,Yim, Y.I.,Canagarajah, B.,Hinshaw, J.E. (deposition date: 2022-09-08, release date: 2023-06-28, Last modification date: 2023-09-13)
Primary citation	Nyenhuis, S.B.,Wu, X.,Strub, M.P.,Yim, Y.I.,Stanton, A.E.,Baena, V.,Syed, Z.A.,Canagarajah, B.,Hammer, J.A.,Hinshaw, J.E. OPA1 helical structures give perspective to mitochondrial dysfunction. Nature, 620:1109-1116, 2023 Cited by PubMed: 37612506 DOI: 10.1038/s41586-023-06462-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.48 Å)

Structure validation