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8EDQ

E. coli pyruvate kinase (PykF) I264F

Summary for 8EDQ
Entry DOI10.2210/pdb8edq/pdb
DescriptorPyruvate kinase, SULFATE ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordspyruvate kinase, long term evolution experiment, kinase, transferase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight102127.14
Authors
Donovan, K.A.,Coombes, D.,Dobson, R.C.J.,Cooper, T.F. (deposition date: 2022-09-05, release date: 2022-11-16, Last modification date: 2023-10-18)
Primary citationDonovan, K.A.,Coombes, D.,Dobson, R.C.J.,Cooper, T.F.
Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.88 Å)
Structure validation

218853

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