8E6V

MHR1/2 and NUDT9H of human TRPM2 in 1 mM dADPR (local refinement)

Summary for 8E6V

• Entry DOI: 10.2210/pdb8e6v/pdb
• Related: 6mj2
• EMDB information: 27927
• Descriptor: Transient receptor potential cation channel subfamily M member 2, ADENOSINE-5-DIPHOSPHORIBOSE, ZINC ION (3 entities in total)
• Functional Keywords: trpm2, trp, adpr, adp-ribose, nudt9h, nudt9, calcium, ion channel, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 172600.23

Authors

Wang, L.,Fu, T.M.,Xia, S.,Wu, H. (deposition date: 2022-08-23, release date: 2024-08-14, Last modification date: 2025-05-28)

• Primary citation: Wang, L.,Fu, T.-M.; A unified mechanism for human TRPM2 activation, desensitization and inhibition; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)