8E6S

Human TRPM2 ion channel in 1 mM dADPR and Ca2+

Summary for 8E6S

• Entry DOI: 10.2210/pdb8e6s/pdb
• Related: 6mj2
• EMDB information: 27924
• Descriptor: Transient receptor potential cation channel subfamily M member 2, ADENOSINE-5-DIPHOSPHORIBOSE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: channel, membrane protein, trpm2, trp, adpr, adp-ribose, nudt9h, nudt9, calcium, ion channel
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 689968.77

Authors

Wang, L.,Fu, T.M.,Xia, S.,Wu, H. (deposition date: 2022-08-23, release date: 2024-08-14, Last modification date: 2025-05-14)

• Primary citation: Wang, L.,Fu, T.-M.; A unified mechanism for human TRPM2 activation, desensitization and inhibition; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.6 Å)