8E51
Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2
Summary for 8E51
Entry DOI | 10.2210/pdb8e51/pdb |
Descriptor | Protocadherin-15, Cadherin-23, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hearing, deafness, cdh23, pcdh15, evolution, tip link, cell adhesion |
Biological source | Pangasianodon hypophthalmus (striped catfish) More |
Total number of polymer chains | 2 |
Total formula weight | 53643.82 |
Authors | Scheib, E.,Nisler, C.R.,Sotomayor, M. (deposition date: 2022-08-19, release date: 2023-03-22, Last modification date: 2024-04-03) |
Primary citation | Nisler, C.R.,Narui, Y.,Scheib, E.,Choudhary, D.,Bowman, J.D.,Mandayam Bharathi, H.,Lynch, V.J.,Sotomayor, M. Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40:-, 2023 Cited by PubMed: 36911992DOI: 10.1093/molbev/msad057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.594 Å) |
Structure validation
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