8E4F
Crystal structure of dihydrofolate reductase (DHFR) from the filarial nematode W. bancrofti in complex with NADPH and folate
Summary for 8E4F
| Entry DOI | 10.2210/pdb8e4f/pdb |
| Descriptor | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FOLIC ACID, ... (5 entities in total) |
| Functional Keywords | reductase, oxidoreductase |
| Biological source | Wuchereria bancrofti |
| Total number of polymer chains | 1 |
| Total formula weight | 23635.58 |
| Authors | Lange, K.,Frey, K.M.,Goodey, N.M. (deposition date: 2022-08-18, release date: 2023-05-10, Last modification date: 2023-10-25) |
| Primary citation | Lange, K.,Frey, K.M.,Eck, T.,Janson, C.A.,Gubler, U.,Goodey, N.M. Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate. Plos Negl Trop Dis, 17:e0011303-e0011303, 2023 Cited by PubMed: 37104530DOI: 10.1371/journal.pntd.0011303 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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