8DZZ
Cryo-EM structure of chi dynein bound to Lis1
Summary for 8DZZ
Entry DOI | 10.2210/pdb8dzz/pdb |
Related | 7MGM 8E00 |
EMDB information | 27810 27811 |
Descriptor | Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | motor protein, dynein |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 6 |
Total formula weight | 895067.96 |
Authors | Reimer, J.M.,Lahiri, I.,Leschziner, A.E. (deposition date: 2022-08-08, release date: 2023-08-30, Last modification date: 2023-09-27) |
Primary citation | Karasmanis, E.P.,Reimer, J.M.,Kendrick, A.A.,Nguyen, K.H.V.,Rodriguez, J.A.,Truong, J.B.,Lahiri, I.,Reck-Peterson, S.L.,Leschziner, A.E. Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30:1357-1364, 2023 Cited by PubMed: 37620585DOI: 10.1038/s41594-023-01069-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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