8DYE

Crystal structure of human SDHA-SDHAF4 assembly intermediate

Summary for 8DYE

Entry DOI	10.2210/pdb8dye/pdb
Descriptor	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase assembly factor 4, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... (8 entities in total)
Functional Keywords	sdha, flavoprotein, sdhaf4, assembly intermediate, respiratory complex, oxidoreductase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	80581.33
Authors	Sharma, P.,Maklashina, E.,Cecchini, G.,Iverson, T.M. (deposition date: 2022-08-04, release date: 2024-01-10, Last modification date: 2024-02-07)
Primary citation	Sharma, P.,Maklashina, E.,Voehler, M.,Balintova, S.,Dvorakova, S.,Kraus, M.,Vanova, K.H.,Nahacka, Z.,Zobalova, R.,Boukalova, S.,Cunatova, K.,Mracek, T.,Ghayee, H.K.,Pacak, K.,Rohlena, J.,Neuzil, J.,Cecchini, G.,Iverson, T.M. Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners. Nat Commun, 15:473-473, 2024 Cited by PubMed: 38212624 DOI: 10.1038/s41467-023-44563-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.44 Å)

Structure validation