8DYE
Crystal structure of human SDHA-SDHAF4 assembly intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | polymer | 611 | 67150.9 | 1 | UniProt (P31040) Pfam (PF00890) Pfam (PF02910) | Homo sapiens (human) | Flavoprotein subunit of complex II,Fp |
| 2 | B (B) | Succinate dehydrogenase assembly factor 4, mitochondrial | polymer | 98 | 11227.4 | 1 | UniProt (Q5VUM1) Pfam (PF07896) | Homo sapiens (human) | SDH assembly factor 4,SDHAF4 |
| 3 | C (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 4 | D (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 5 | E, F, G, H, J... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 6 | I, M, R (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | X, Y (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | AA, Z (B, A) | water | water | 18.0 | 422 | Chemie (HOH) |
Sequence modifications
B: 34 - 108 (UniProt: Q5VUM1)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | initiating methionine |
| Arg 12 | - | expression tag |
| Ser 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Asn 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Tyr 23 | - | expression tag |
| Phe 24 | - | expression tag |
| Gln 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ile 27 | - | expression tag |
| Asp 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Phe 30 | - | expression tag |
| Thr 31 | - | expression tag |
| Gly 32 | - | expression tag |
| Ser 33 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78378.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 2202.9 | |
| All* | Total formula weight | 80581.3 |
