8DYD
Crystal structure of human SDHA-SDHAF2-SDHAF4 assembly intermediate
Summary for 8DYD
Entry DOI | 10.2210/pdb8dyd/pdb |
Descriptor | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase assembly factor 2, mitochondrial, Succinate dehydrogenase assembly factor 4, mitochondrial, ... (10 entities in total) |
Functional Keywords | sdha, flavoprotein, sdhaf2, sdhaf4, assembly intermediate, respiratory complex, oxidoreductase, electron transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 100559.51 |
Authors | Sharma, P.,Maklashina, E.,Cecchini, G.,Iverson, T.M. (deposition date: 2022-08-04, release date: 2024-01-10, Last modification date: 2024-02-07) |
Primary citation | Sharma, P.,Maklashina, E.,Voehler, M.,Balintova, S.,Dvorakova, S.,Kraus, M.,Vanova, K.H.,Nahacka, Z.,Zobalova, R.,Boukalova, S.,Cunatova, K.,Mracek, T.,Ghayee, H.K.,Pacak, K.,Rohlena, J.,Neuzil, J.,Cecchini, G.,Iverson, T.M. Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners. Nat Commun, 15:473-473, 2024 Cited by PubMed: 38212624DOI: 10.1038/s41467-023-44563-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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