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8DY8

Crystal structure of the R178Q mutant of ubiquitin carboxy terminal hydrolase L1 (UCH-L1)

Summary for 8DY8
Entry DOI10.2210/pdb8dy8/pdb
DescriptorUbiquitin carboxyl-terminal hydrolase isozyme L1, SULFATE ION, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsdeubiquitinase, cysteine hydrolase, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight50787.96
Authors
Kenny, S.,Brown, K.J.,Das, C. (deposition date: 2022-08-03, release date: 2023-08-09, Last modification date: 2026-03-04)
Primary citationKenny, S.,Brown, K.J.,Das, C.
Enhanced catalytic activity of the UCHL1R178Q mutant is due to a more reactive active site
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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