8DXQ
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4
Summary for 8DXQ
Entry DOI | 10.2210/pdb8dxq/pdb |
Related | 8DXN 8DXO 8DXP |
EMDB information | 27773 |
Descriptor | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A (1 entity in total) |
Functional Keywords | lrrc8c, lrrc8a, swell, vrac, chimera, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 663233.86 |
Authors | Takahashi, H.,Yamada, T.,Denton, J.S.,Strange, K.,Karakas, E. (deposition date: 2022-08-02, release date: 2023-03-22, Last modification date: 2024-06-12) |
Primary citation | Takahashi, H.,Yamada, T.,Denton, J.S.,Strange, K.,Karakas, E. Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12:-, 2023 Cited by PubMed: 36897307DOI: 10.7554/eLife.82431 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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