8DXQ
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | polymer | 825 | 94747.7 | 7 | UniProt (Q8TDW0) UniProt (Q8IWT6) Pfam (PF12534) Pfam (PF13855) | Homo sapiens (human) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C,Leucine-rich repeat-containing protein 8A,HsLRRC8A,Swelling protein 1 |
Sequence modifications
A, B, C, D, E, F, G: 1 - 176 (UniProt: Q8TDW0)
A, B, C, D, E, F, G: 176 - 177 (UniProt: Q8IWT6)
A, B, C, D, E, F, G: 177 - 802 (UniProt: Q8TDW0)
A, B, C, D, E, F, G: 176 - 177 (UniProt: Q8IWT6)
| PDB | External Database | Details |
|---|---|---|
| Gly 177 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| - | Lys 717 | deletion |
| Glu 803 | - | expression tag |
| Asn 804 | - | expression tag |
| Leu 805 | - | expression tag |
| Tyr 806 | - | expression tag |
| Phe 807 | - | expression tag |
| Gln 808 | - | expression tag |
| Gly 809 | - | expression tag |
| Ala 810 | - | expression tag |
| Ala 811 | - | expression tag |
| Ala 812 | - | expression tag |
| Gly 813 | - | expression tag |
| Asp 814 | - | expression tag |
| Tyr 815 | - | expression tag |
| Lys 816 | - | expression tag |
| Asp 817 | - | expression tag |
| Asp 818 | - | expression tag |
| Asp 819 | - | expression tag |
| Asp 820 | - | expression tag |
| Lys 821 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 663233.9 | |
| All* | Total formula weight | 663233.9 |
