8DS8
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Summary for 8DS8
Entry DOI | 10.2210/pdb8ds8/pdb |
Descriptor | Trinucleotide repeat-containing gene 18 protein, Histone H3.1 (3 entities in total) |
Functional Keywords | protein complex, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 47931.10 |
Authors | Song, J.K.,Lu, J.W. (deposition date: 2022-07-21, release date: 2023-08-02, Last modification date: 2023-11-29) |
Primary citation | Zhao, S.,Lu, J.,Pan, B.,Fan, H.,Byrum, S.D.,Xu, C.,Kim, A.,Guo, Y.,Kanchi, K.L.,Gong, W.,Sun, T.,Storey, A.J.,Burkholder, N.T.,Mackintosh, S.G.,Kuhlers, P.C.,Edmondson, R.D.,Strahl, B.D.,Diao, Y.,Tackett, A.J.,Raab, J.R.,Cai, L.,Song, J.,Wang, G.G. TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature, 623:633-642, 2023 Cited by PubMed: 37938770DOI: 10.1038/s41586-023-06688-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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