8DPW
The structure of Interleukin-11 Mutein
Summary for 8DPW
Entry DOI | 10.2210/pdb8dpw/pdb |
Descriptor | Interleukin-11, SULFATE ION (3 entities in total) |
Functional Keywords | complex, cytokine, il-6 family cytokine |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 18396.36 |
Authors | Metcalfe, R.D.,Griffin, M.D.W. (deposition date: 2022-07-17, release date: 2023-11-29, Last modification date: 2024-05-01) |
Primary citation | Metcalfe, R.D.,Hanssen, E.,Fung, K.Y.,Aizel, K.,Kosasih, C.C.,Zlatic, C.O.,Doughty, L.,Morton, C.J.,Leis, A.P.,Parker, M.W.,Gooley, P.R.,Putoczki, T.L.,Griffin, M.D.W. Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14:7543-7543, 2023 Cited by PubMed: 37985757DOI: 10.1038/s41467-023-42754-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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