8DPW
The structure of Interleukin-11 Mutein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-11 | polymer | 169 | 18300.3 | 1 | UniProt (P20809) Pfam (PF07400) | Homo sapiens (human) | IL-11,Adipogenesis inhibitory factor,AGIF |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 11 - 178 (UniProt: P20809)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
| Pro 58 | Ala 79 | engineered mutation |
| Ala 59 | Met 80 | engineered mutation |
| Ile 60 | Ser 81 | engineered mutation |
| Asp 61 | Ala 82 | engineered mutation |
| Tyr 62 | Gly 83 | engineered mutation |
| Ala 147 | Trp 168 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18300.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 18396.4 |
