8DNQ
BRD2-BD1 in complex with cyclic peptide 2.2B
Summary for 8DNQ
Entry DOI | 10.2210/pdb8dnq/pdb |
Descriptor | Bromodomain-containing protein 2, Cyclic peptide 2.2B, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cyclic peptide, bromodomain, brd2, bet, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 36228.06 |
Authors | Patel, K.,Franck, C.,Mackay, J.P. (deposition date: 2022-07-11, release date: 2023-07-19, Last modification date: 2023-12-06) |
Primary citation | Franck, C.,Patel, K.,Walport, L.J.,Christie, M.,Norman, A.,Passioura, T.,Suga, H.,Payne, R.J.,Mackay, J.P. Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins. Structure, 31:912-923.e4, 2023 Cited by PubMed: 37269828DOI: 10.1016/j.str.2023.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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