8DNQ
BRD2-BD1 in complex with cyclic peptide 2.2B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain-containing protein 2 | polymer | 135 | 15765.3 | 2 | UniProt (U3KQA6) Pfam (PF00439) UniProt (by SIFTS) (P25440) In PDB | Homo sapiens (human) | BRD2 |
| 2 | C, D | Cyclic peptide 2.2B | polymer | 17 | 2118.5 | 2 | synthetic construct | ||
| 3 | A, B, C | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 65 - 194 (UniProt: U3KQA6)
| PDB | External Database | Details |
|---|---|---|
| Gly 60 | - | expression tag |
| Pro 61 | - | expression tag |
| Leu 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Ser 64 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35767.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 36228.1 |
