8DJG

ADGRL3-lectin domain in complex with an activating synthetic antibody fragment

8DJG の概要

• エントリーDOI: 10.2210/pdb8djg/pdb
• 分子名称: sAB Heavy Chain, sAB Light Chain, Isoform 2 of Adhesion G protein-coupled receptor L3, ... (7 entities in total)
• 機能のキーワード: adhesion gpcr, lectin domain, sab, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 121717.78

構造登録者

Kordon, S.P.,Bandekar, S.J.,Arac, D. (登録日: 2022-06-30, 公開日: 2023-02-15, 最終更新日: 2023-10-25)

• 主引用文献: Kordon, S.P.,Dutka, P.,Adamska, J.M.,Bandekar, S.J.,Leon, K.,Erramilli, S.K.,Adams, B.,Li, J.,Kossiakoff, A.A.,Arac, D.; Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.; Nat Commun, 14:635-635, 2023; PubMed: 36746957; DOI: 10.1038/s41467-023-36312-7

実験手法

X-RAY DIFFRACTION (2.65 Å)