8DHA
Leptin-bound leptin receptor complex- focused interaction
Summary for 8DHA
Entry DOI | 10.2210/pdb8dha/pdb |
EMDB information | 27434 |
Descriptor | Leptin receptor, Leptin, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | leptin, receptor, complex, hormone |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 143351.75 |
Authors | Saxton, R.A.,Caveney, N.A.,Garcia, K.C. (deposition date: 2022-06-25, release date: 2023-04-19, Last modification date: 2024-10-09) |
Primary citation | Saxton, R.A.,Caveney, N.A.,Moya-Garzon, M.D.,Householder, K.D.,Rodriguez, G.E.,Burdsall, K.A.,Long, J.Z.,Garcia, K.C. Structural insights into the mechanism of leptin receptor activation. Nat Commun, 14:1797-1797, 2023 Cited by PubMed: 37002197DOI: 10.1038/s41467-023-37169-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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