8DDL

SARS-CoV-2 Main Protease (Mpro) H163A Mutant Apo Structure

Summary for 8DDL

• Entry DOI: 10.2210/pdb8ddl/pdb
• Related: 8DD6
• Descriptor: ORF1a polyprotein, TRIETHYLENE GLYCOL, SODIUM ION, ... (7 entities in total)
• Functional Keywords: cysteine protease, sars-cov-2, 3cl-like, disulfide bond, viral protein, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 68130.60

Authors

Tran, N.,McLeod, M.J.,Kalyaanamoorthy, S.,Ganesan, A.,Holyoak, T. (deposition date: 2022-06-18, release date: 2023-06-28, Last modification date: 2023-11-15)

• Primary citation: Tran, N.,Dasari, S.,Barwell, S.A.E.,McLeod, M.J.,Kalyaanamoorthy, S.,Holyoak, T.,Ganesan, A.; The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease.; Nat Commun, 14:5625-5625, 2023; PubMed: 37699927; DOI: 10.1038/s41467-023-40023-4

Experimental method

X-RAY DIFFRACTION (1.95 Å)