8DDL
SARS-CoV-2 Main Protease (Mpro) H163A Mutant Apo Structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ORF1a polyprotein | polymer | 306 | 33758.5 | 1 | UniProt (A0A7U3EDN3) Pfam (PF05409) UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (B) | ORF1a polyprotein | polymer | 306 | 33774.5 | 1 | UniProt (A0A7U3EDN3) Pfam (PF05409) UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | C, E (A, B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | F, G (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | H (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A: 1 - 306 (UniProt: A0A7U3EDN3)
B: 1 - 306 (UniProt: A0A7U3EDN3)
| PDB | External Database | Details |
|---|---|---|
| Ala 163 | His 3404 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 163 | His 3404 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67533.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 597.6 | |
| All* | Total formula weight | 68130.6 |
