8DB8
Adenosine/guanosine nucleoside hydrolase bound to ImH
Summary for 8DB8
Entry DOI | 10.2210/pdb8db8/pdb |
Descriptor | Inosine-uridine preferring nucleoside hydrolase family protein, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | nucleoside, hydrolase, adenosine, guanosine, parasitic, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Trichomonas vaginalis |
Total number of polymer chains | 4 |
Total formula weight | 134598.16 |
Authors | Muellers, S.N.,Allen, K.N.,Stockman, B.J. (deposition date: 2022-06-14, release date: 2022-09-07, Last modification date: 2024-04-03) |
Primary citation | Muellers, S.N.,Nyitray, M.M.,Reynarowych, N.,Saljanin, E.,Benzie, A.L.,Schoenfeld, A.R.,Stockman, B.J.,Allen, K.N. Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase. Biochemistry, 61:1853-1861, 2022 Cited by PubMed: 35994320DOI: 10.1021/acs.biochem.2c00361 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
Download full validation report