8D42
Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (composite)
Summary for 8D42
Entry DOI | 10.2210/pdb8d42/pdb |
EMDB information | 27154 27155 27163 27169 27170 27171 27172 |
Descriptor | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, DNA (5'-D(P*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ... (6 entities in total) |
Functional Keywords | dna-binding protein, dna polymerase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 266004.21 |
Authors | |
Primary citation | Park, J.,Herrmann, G.K.,Mitchell, P.G.,Sherman, M.B.,Yin, Y.W. Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30:812-823, 2023 Cited by PubMed: 37202477DOI: 10.1038/s41594-023-00980-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.91 Å) |
Structure validation
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