8D41

Crystal structure of the human COPB2 WD-domain in complex with OICR-6254

Summary for 8D41

• Entry DOI: 10.2210/pdb8d41/pdb
• Descriptor: Coatomer subunit beta', (1R,2R,3S,4S)-3-[4-(4-fluorophenyl)piperazine-1-carbonyl]bicyclo[2.2.1]heptane-2-carboxylic acid, GLYCEROL, ... (5 entities in total)
• Functional Keywords: wd-repeat, wdr, copb2, coatomer subunit beta, sgc, structural genomics, structural genomics consortium, protein transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 73702.40

Authors

Zeng, H.,Saraon, P.,Dong, A.,Hutchinson, A.,Seitova, A.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2022-06-01, release date: 2022-07-06, Last modification date: 2023-10-18)

• Primary citation: Zeng, H.,Saraon, P.,Dong, A.,Hutchinson, A.,Seitova, A.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Crystal structure of the human COPB2 WD-domain in complex with OICR-6254; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)