8D41
Crystal structure of the human COPB2 WD-domain in complex with OICR-6254
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Coatomer subunit beta' | polymer | 318 | 36421.2 | 2 | UniProt (P35606) Pfam (PF00400) In PDB | Homo sapiens (human) | Beta'-coat protein,Beta'-COP,p102 |
2 | A, B | (1R,2R,3S,4S)-3-[4-(4-fluorophenyl)piperazine-1-carbonyl]bicyclo[2.2.1]heptane-2-carboxylic acid | non-polymer | 346.4 | 2 | Chemie (Q93) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | A | UNKNOWN ATOM OR ION | non-polymer | 75.1 | 1 | Chemie (UNX) | |||
5 | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: P35606)
PDB | External Database | Details |
---|---|---|
Met -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Arg -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 72842.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 860.0 | |
All* | Total formula weight | 73702.4 |